Researching how diet affects health is not an easy task and often starts with studies involving animals. Researchers will often use a mouse model of MS called experimental autoimmune encephalomyelitis (EAE) to test how different interventions affect the immune system or disease symptoms. In the MS community, we often joke that it is the mice that get all the cures. Translating their cures into human treatments has been a huge challenge.
Researchers at the University of Southern California investigating the role of diet interventions in MS found that a fasting-mimicking diet (FMD) promotes neuro-regeneration, reduces autoimmunity, and reduces symptoms in a mouse model of MS. They found that the FMD reduced the severity of clinical symptoms in all study mice and completely reversed symptoms in 20 percent of the animals. The improvements seen with FMD were associated with reduced levels of pro-inflammatory cytokines, increased corticosterone levels, and increased production of oligodendrocyte cells that encouraged remyelination (Choi et al, 2016).
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Diet That Mimics Fasting May Reduce MS Symptoms
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